Relationship Between Neointimal Thickness and Shear Stress After Wallstent Implantation in Human Coronary Arteries
نویسندگان
چکیده
منابع مشابه
Relationship between neointimal thickness and shear stress after Wallstent implantation in human coronary arteries.
BACKGROUND In-stent restenosis by excessive intimal hyperplasia reduces the long-term clinical efficacy of coronary stents. Because shear stress (SS) is related to plaque growth in atherosclerosis, we investigated whether variations in SS distribution are related to variations in neointima formation. METHODS AND RESULTS In 14 patients, at 6-month follow-up after coronary Wallstent implantatio...
متن کاملAlterations in wall shear stress predict sites of neointimal hyperplasia after stent implantation in rabbit iliac arteries.
Restenosis resulting from neointimal hyperplasia (NH) limits the effectiveness of intravascular stents. Rates of restenosis vary with stent geometry, but whether stents affect spatial and temporal distributions of wall shear stress (WSS) in vivo is unknown. We tested the hypothesis that alterations in spatial WSS after stent implantation predict sites of NH in rabbit iliac arteries. Antegrade i...
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BACKGROUND Low wall shear stress (WSS) increases neointimal hyperplasia (NH) in vein grafts and stents. We studied the causal relationship between WSS and NH formation in stents by locally increasing WSS with a flow divider (Anti-Restenotic Diffuser, Endoart SA) placed in the center of the stent. METHODS AND RESULTS In 9 rabbits fed a high-cholesterol diet for 2 months to induce endothelial d...
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INTRODUCTION AND OBJECTIVES Intravascular ultrasound (IVUS) studies in conventional stent angioplasty with predilatation have demonstrated that late luminal narrowing is caused by neointimal proliferation. In the present study, we analyzed the degree and distribution of in-stent neointimal proliferation after direct stent implantation and aimed to identify variables that predict a proliferative...
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Objective: To investigate the relationship between atherosclerosis of carotid arteries and coronary arteries. Methods: This was a cross-sectional case control study and 100 patients took part in it. All participants underwent angiography to determine if they had coronary stenosis. Fifty angiography positive patients were selected as case and 50 angiography negative served as control. With a 7 M...
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ژورنال
عنوان ژورنال: Circulation
سال: 2001
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.103.13.1740